Three-colour flow cytometric analysis of lymph node cells for a typical case of follicle centre lymphoma. A proportion of cells express CD10 in combination with CD38. There is light chain restriction with almost all the cells expressing sIg-kappa. The other main immunophenotypic features are the presence of either IgM or IgG with CD19, CDw75 and CD20. CD23 is present in some cases. CD45RA is often aberrantly expressed in follicle centre lymphoma.

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